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92 shown that enhanced preload could lead to elevated myocyte Ca2+-entry secondary to mechanical pressure unbiased of ischaemia, Consequently bringing about activation of μ-calpains and calpain-mediated cTnI proteolysis.
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Elevations in cTnI and cTnT ranges arise in people with coronary heart failure, in both equally the acute decompensated191,192 period along with the secure period.
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